CHEMICAL AND MINERALOGICAL CHARACTERIZATION AND ANTI-INFLAMMATORY ACTIVITY EVALUATION OF SENEGAL....

Clays have long been used in treatments, and the spread of thermal mud centres attests to their efficacy. After chemical and mineralogical characterisation, the anti-inflammatory potential of Ziguinchor mangrove sludge and Mbodiène attapulgite was assessed in this study. The findings revealed that mangrove mud contains numerous components with varied salt, aluminium, chlorine, silicon, and iron levels. Silicon 55.15 percent, magnesium 13.8 percent, calcium 11.11 percent, iron 8.3 percent, and aluminium 7.78 percent made up the majority of attapulgite. The cation exchange capacity of Attapulgite was 95 meq / 100 g when measured with the cobaltihexamine ion, compared to 6.85 meq / 100 g for the mangrove mud. According to mineralogical investigation, mangrove mud is primarily composed of kaolinite, with palygorskite as the dominating mineral of attapulgite, along with quartz, ankerite crystals, and dolomites. The proportion of inhibition of edoema caused in croton oil ranged from 25.23 percent for attapulgite to 28.34 percent for Ziguinchor mud, compared to 52.26 percent for Voltaren Emulgel® as a reference. These findings point to a good option to provide additional treatment for diseases like osteoarthritis at a cheaper cost.

Please see the link :- https://www.ikprress.org/index.php/JACSI/article/view/3819