ISOLATION OF SECONDARY METABOLITES FROM PAKU ATAI MERAH (Angiopteris ferox Copel) TUBERS | PLANT ..

Context and Identity: The tuber of the fern plant Paku atai merah (Angiopteris ferox Copel) has been used empirically as a traditional medicine in culture. The tuber is the most commonly used component of the plant. However, the secondary metabolite content of this plant is unknown scientifically. The aim of this research was to find out what secondary metabolites could be found in paku atai merah tubers. Methodologies: The sample was collected using an ethanol solvent maceration process, fractionated using traditional column chromatography, and characterised using Nuclear Magnetic Resonance (NMR). As many as 13 fractions were obtained using the chromatographic column as a fractionator. The optimum separation from fraction 4 (F4) was obtained from the fraction.The results of the separation from F4 yielded 17 sub-fractions in total (F1-F17).

F7 and F8 sub-fractions showed good purity, and characterization results revealed that F7and F8 were the same compounds, namely Angiopteroside compounds. Conclusion: This research contributes to the discovery of a secondary metabolite in the form of Angiopteroside in the Angiopteris ferox Copel genus, which can be used in the development of new drugs.

Please see the link - https://www.ikprress.org/index.php/PCBMB/article/view/5726