PHYTOCHEMICAL ANALYSIS AND BIOLOGICAL ACTIVITIES OF Cirsium verutum AND Meconopsis aculeate | PLANT

Many scientific reports and investigations have verified the presence of many types of secondary metabolites and phytochemicals in medicinal plants that offer a wide range of benefits for human health and nutrition. Cirsium verutum and Meconopsis aculeate are two medicinal plants found in Himalayan regions that are utilised in traditional Tibetan medicine in various herbal compositions. The presence of numerous types of possible secondary metabolites was shown by phytochemical analysis and biological activities of C. verutum and M. aculeate extracted from six different solvents. C. verutum had the highest total phenolic content (TPC) in ethanol extracts, with 6.877 0.013 mg/GAE g, and M. aculeata had the highest total flavonoid content (TFC) in ethyl acetate extracts, with 15.6370.085 mg/QE g. The ethanol extracts of C. verutum had the highest free radical scavenging activity, with around 95% activity, as measured by DPPH. Both plant samples were effective against bacterium and fungal cultures, according to antibacterial activity. 2.50 g/ml was the minimum inhibitory concentration (MIC) against bacteria and fungus.

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