STUDY OF ANTIMICROBIAL PEPTIDES EXTRACTED FROM CYANOBACTERIUM, Spirulina sp. | Asian Journal

The importance of porous scaffolds in tissue engineering applications cannot be overstated. Metallic scaffolds, in particular, are being investigated. As a biodegradable metal, zinc is an alternative to magnesium. Zn has a faster rate of biodegradation than Mg. Recent research has confirmed that Zn is harmless and capable of osseointegration. The melting temperature, machinability, and reactivity of zinc alloys are all low. Biodegradable Zn alloy was created for scaffold and temporary implant applications in this study. The powder metallurgy-based space holder method was used to create samples with linked porous structures. Zn and Mg powders were used to make Zn-Mg alloys. The powder mixes were processed with a ball mill. As a space holder, carbamide granules were utilised. After immersing the samples in the water, the space holder was removed. Under argon, sintering was carried out at 400°C for 1 hour. The samples had lower corrosion rates than the Mg alloys, according to the findings. Weight loss and metal release measures were also used to evaluate biodegradation. There was a 2-4 percent weight decrease. The amount of metal released was less than the Zn daily maximum limit of 15 mg/day. The strength of Zn was enhanced by alloying. Mg increased osseointegration and biocompatibility qualities. With an increase in Mg concentration, the modulus of elasticity increased by 24%.

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