THE IMPACT OF PLANT EXTRACTS ON THE METABOLIC PROFILE OF ENDOPHYTIC FUNGI ISOLATED FROM VINCA PLANTS

The effect of Vinca rosea complete extract on the development of vinca alkaloids by endophytic fungi Aspergillus amstelodami-VR177L and Penicillium concavoradulozum-VE89L was investigated. The plant extract has a positive effect on the development, level of vinblastine, and antibacterial activity of the associated endophyte Aspergillus amstelodami–VR177L, while having a negative effect on the same parameters of Penicillium concavoradulozum-VE89L, isolated from the related plant Vinca erecta.

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