THE RELATIONSHIP BETWEEN TWO BIOCHEMICAL MARKERS OF OXIDATIVE STRESS USED FOR ASSESSING POLLUTION...

The primary goal of this paper was to assess the health of marine waters in Mohammedia (Morocco) using oxidative stress measures and to investigate their relationship in sentinel species, Perna perna. Catalase (CAT), an antioxidant enzyme representing the cellular defence mechanisms that counteract the toxicity of reactive oxygen species, and malondialdehyde (MDA), a metabolite indicating generic oxidative stress caused by an excess of membrane lipid peroxidation and considered to be one of the primary key events in oxidative damage, were used as biomarkers in this study. The ANOVA results for CAT activity and MDA level revealed statistically significant differences (p 0.05) in the studied specie issuing from the polluted site (S2) in comparison to the control values of station 1 (S1), chosen as a suitable clean area (22,356,358 against 12,3121,820 nmol/min/mg proteins (p=0,0004; dft=9) and 4,8381,217 against 2,2340,115 nmol/min/m The MDA level was shown to have a positive association with CAT activity (r = 0,909, p = 0,032; dft=4) in S2, but an insignificant negative correlation with reference site (S1) (r = - 0,389, p = 0,517; dft=4). Our findings clearly show that organisms from S2 were exposed to contaminants in situ. The brown mussel was used as a sentinel species in this work to demonstrate that CAT and MDA might be detected for biomonitoring the environmental health of the Moroccan coast.

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